17-OH-Progesterone GENLISA ELISA

Introduction: The steroid 17 Hydroxyprogesterone (17-OH P) is produced by both the adrenal cortex and gonads. It is synthesised from progesterone and serves primarily as a precursor compound that is converted into cortisol in the adrenal gland, or into androgenic and estrogenic steroid hormones in the gonads. Even though 17-a-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). CpS is formed by hydroxylation of the carbon atom C 21. Enzyme activity of 21- hydroxylase in the adrenal cortex may thus be monitored by analyzing the level of 17-OHP in the blood.