Leptospira IgM GENLISA™ ELISA

Introduction: Leptospirosis is considered an emerging zoonotic disease of global importance and is found in both urban and rural areas of affected countries. It is caused by the genus Leptospira. which are motile spirochaetes of which there are 16 genomo-species as delineated by DNA?DNA hybridization. Transmission to humans occurs through penetration of the organism into the blood stream via cuts, skin abrasions or mucus membranes. Infection may range in presentation from subclinical to severe . Onset is usually sudden, with symptoms including headache, fever, muscle pains, conjunctival infection, meningitis and abdominal pains. Severe complications such as hepato-renal failure and central nervous system involvement may arise. It is also known as ?Weil’s syndrome.?